| 麻醉对腰椎间盘突出症手术病人T淋巴细胞亚群的影响 |
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| 引用本文： | 黄秀玲,王健,朱建林. 麻醉对腰椎间盘突出症手术病人T淋巴细胞亚群的影响[J]. 齐鲁医学杂志, 2006, 21(6): 517-518 |
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| 作者姓名： | 黄秀玲 王健 朱建林 |
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| 作者单位： | 青岛大学医学院附属医院检验科,山东,青岛266003;青岛市海慈医院检验科;即墨市人民医院骨科 |
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| 摘 要： | 目的研究不同麻醉方法对围手术期腰椎间盘突出症病人细胞免疫功能的影响。方法应用流式细胞仪,对58例采用局麻和硬膜外麻醉方法接受腰椎间盘髓核摘除术病人术前、术后第1天以及术后第3天的T淋巴细胞亚群进行测定及比较分析。结果术后第1天,采用两种不同麻醉方法的手术病人CD4 亚群数量下降,CD4 /CD8 比值下降(t=2.220~3.450,P<0.05);术后第3天恢复到术前水平;两组病人在同一时段的CD4 、CD8 水平差别无统计学意义(P>0.05)。结论两种麻醉方法都能获得满意的手术效果,对手术病人的细胞免疫功能影响没有差别。
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| 关 键 词： | 麻醉 椎间盘移位 T淋巴细胞亚群 |
| 文章编号： | 1008-0341(2006)06-0517-02 |
| 收稿时间： | 2006-05-22 |
| 修稿时间： | 2006-07-10 |
EFFECT OF DIFFERENT ANESTHESIA ON T-LYMPHOCYTE SUBTYPE IN PATIENTS UNDERGOING OPERATION FOR LUMBAR DISC HERNIATION |
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| HUANG XIU-LING,WANG JIAN,ZHU JIAN-LIN. EFFECT OF DIFFERENT ANESTHESIA ON T-LYMPHOCYTE SUBTYPE IN PATIENTS UNDERGOING OPERATION FOR LUMBAR DISC HERNIATION[J]. Medical Journal of Qilu, 2006, 21(6): 517-518 |
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| Authors: | HUANG XIU-LING WANG JIAN ZHU JIAN-LIN |
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| Affiliation: | Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University Medical College, Qingdao 266003, China |
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| Abstract: | ObjectiveTo study the influences of different anesthesia on the cellular immunity in perioperative patients with lumbar disc herniation.MethodsFifty-eight patients with lumbar disc herniation who had received discectomy under diffe-(rent) anesthesia were studied.Peripheral blood samples were taken at different times preoperatively and postoperatively.CD~ _4 and CD~ _8 positive lymphocyte subtypes were measured.ResultsThe levels of CD~ _4 and CD~ _4/CD~ _8 ratio were all decreased(t=(2.220-)3.450,P<0.05) on the first day after operation and became normal on the third day.ConclusionThe influences of different anesthesia on CD~ _4 and CD~ _8 positive lymphocyte subtypes are not significantly different. |
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| Keywords: | anesthesia intervertebral disk displacement T-lymphocyte subsets |
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