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Contrast-Enhanced Ultrasound (CEUS) in the Evaluation of Hemoperitoneum in Patients With Cirrhosis
Authors:Farid Abushamat MD  Christoph F. Dietrich MD  MBA  Dirk-Andre Clevert MD  Fabio Piscaglia MD  PhD  David T. Fetzer MD  Maria Franca Meloni MD  Masoud Shiehmorteza MD  Yuko Kono MD  PhD
Affiliation:1. University of California San Diego, San Diego, CA, USA;2. Clinic Hirslanden Bern Beau Site, Bern, Switzerland;3. University of Munich-Grosshadern Campus, Munich, Germany;4. Division of Internal Medicine, Hepatobiliary and Immunoallergic Diseases, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy;5. UT Southwestern Medical Center, Dallas, TX, USA;6. University of Milan-Bicocca, Milan, Italy
Abstract:Hemoperitoneum in cirrhosis is a life-threatening condition that requires emergent evaluation. Contrast-enhanced ultrasound (CEUS) permits multiple dynamic characterizations of abdominal structures through all vascular phases, and contrast extravasation or the presence of microbubbles in the ascites could be a sensitive tool. We reviewed 13 patients with cirrhosis that underwent CEUS due to high suspicion for intra-abdominal bleeding. In 10 cases, CEUS demonstrated extravasation of contrast, including 2 instances where CEUS detected active bleeding despite negative computed tomography. These data support further study of CEUS in direct comparison to other imaging modalities in this clinical context.
Keywords:CEUS  cirrhosis  bleeding  hemoperitoneum
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