| 中药复方掩味技术初步研究 |
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| 引用本文： | 王优杰,冯怡,徐德生. 中药复方掩味技术初步研究[J]. 中国中药杂志, 2007, 32(13): 1285-1288 |
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| 作者姓名： | 王优杰 冯怡 徐德生 |
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| 作者单位： | 1. 上海中医药大学,科技中心,上海,201203
2. 上海中医药大学,中药学院,上海,201203 |
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| 基金项目： | 上海市重点学科建设项目 |
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| 摘 要： | 目的：作者以复方双黄连为模型药物,采用喷雾干燥法制备微球,达到掩味目的。方法：追踪复方苦味来源,建立复方苦味标准曲线,并以苦味评价、收率和包封率为指标筛选掩味处方及掩味微球制备工艺考察。结果：复方中的苦味主要来自连翘,Eudargit E100为最佳掩味材料,最佳喷雾干燥的工艺参数为：待喷液浓度2%、进风温度75 ℃、进风风量35 m3·h-1、喷雾风量0.35 m3·h-1、进液速度8 mL·min-1。结论：喷雾干燥法可以作为一种中药复方的掩味技术,工艺简单,掩味效果好,有较强的实用价值。
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| 关 键 词： | 掩味 喷雾干燥 微球 |
| 文章编号： | 1001-5302（2007）13-1285-04 |
| 收稿时间： | 2006-06-14 |
| 修稿时间： | 2006-06-14 |
Studies on taste-masking technology of traditional Chinese medicine compounds |
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| WANG You-jie; FENG Yi; XU De-sheng. Studies on taste-masking technology of traditional Chinese medicine compounds[J]. China Journal of Chinese Materia Medica, 2007, 32(13): 1285-1288 |
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| Authors: | WANG You-jie FENG Yi XU De-sheng |
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| Affiliation: | (Shanghai University of Traditional Chinase Madicine, Shanghai 201203, China. |
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| Abstract: | OBJECTIVE: To investigate the preparation of Shuanghuanglian taste-masking microspheres by spray-drying. METHOD: Traced the compounds bitterness source, marked its curve and optimized the microspheres preparation by taking taste evaluation, microspheres yield and inclusion rate as the indexes. RESULT: The bitter taste of compounds comes from Forsythia suspensa. The best taste-masking material is Eudragit E100. The optimal spray-drying parameters: solvent concentration 2.0%, inlet air temperature 75 degrees C, aspirator 35.0 m3 x h(-1), spray flow 0.35 m3 x h(-1), pump speed 8.0 mL x min(-1). CONCLUSION: The spray-drying as a method of masking the traditional Chinese medicine compound taste have advantages of simple process and efficient masking. |
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| Keywords: | Eudargit E100 |
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