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No Association of Phenotypic ABO Blood Group and Malaria during Pregnancy
Authors:Machteld E Boel  Marcus J Rijken  Mupawjay Pimanpanarak  Naw Lily Keereecharoen  Stephane Proux  François Nosten  Rose McGready
Affiliation:Shoklo Malaria Research Unit, Mae Sot, Tak, Thailand; Academic Medical Center, Amsterdam, The Netherlands; Faculty of Tropical Medicine, Mahidol University, Thailand; Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom.
Abstract:Abstract. In a few small studies an association between blood group O and placental malaria has been described. The relationship between blood group and malaria in pregnancy (Plasmodium vivax and Plasmodium falciparum) was analyzed in 1,468 women from three longitudinal cohort studies in which weekly malaria screening was done systematically during pregnancy. One-third of women (447 of 1,468) had at least one malaria infection in pregnancy. The ABO blood group phenotype was not associated with the species of infection, frequency of malaria attacks, symptoms of malaria, hematocrit, or parasitemia during pregnancy.
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