Role of different forms of basic fibroblast growth factor and transforming growth factor in the development of nephrotoxic nephritis in rats |
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| Authors: | K. V. Opalenov O. P. Gladskikh E. M. Pal'tseva A. A. Ivanov |
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| Affiliation: | (1) Department of Pathological Anatomy, Ist Therapeutic and Preventive Faculty, Laboratory of Cellular and Molecular Pathology, Research Center of I. M. Sechenov Moscow Medical Academy, Moscow |
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| Abstract: | The modeling of rat nephrotoxic nephritis showed that the development of matrixassociated forms of basic fibroblast growth factor and transforming growth factor-β1 can be one of the mechanisms regulating their activity. Disturbances in the development of these associated complexes may result in glomerulosclerosis. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 126, No. 7, pp. 107–109, July, 1998 |
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| Keywords: | basic fibroblast growth factor transforming growth factor-β 1 extracellular matrix nephrotoxic nephritis |
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