常规机械通气对海水淹溺型肺水肿的治疗作用

目的观察常规机械通气（CMV）治疗兔海水型肺水肿（PE-SWD）的效果。方法应用CMV对14只PE．SWD新西兰大白兔进行救治，观察治疗后血气分析、肺损伤指标、病理学的改善情况，并观察部分呼吸动力学、血流动力学指标。结果CMV通气治疗后PE—SWD免动脉血氧分压（PaO2）、血氧饱和度（SaO2）、二氧化碳分压（PaCO2）均较未治疗组有明显改善（均P〈0．01），呼吸动力学、血流动力学异常得到一定程度纠正，通气治疗后肺损伤程度减轻。结论CMV通气治疗PE—SWD时低氧血症效果满意。

The therapeutic effect of conventional mechanical ventilation on pulmonary edema after seawater drowning

Objective To observe the therapeutic effect of conventional mechanical ventilation (CMV) on pulmonary edema after seawater drowning in rabbits(PE-SWD).Methods Fourteen seawater lavage induced pulmonary edema New Zealand rabbits models were randomly assigned to receive CMV treatment.Blood gas analysis, pulmodynamic, hemodynamics status were monitored. Results PaO_2 and SaO_2 were significantly increased after the use of ventilation in PE-SWD(P<0.01).Pulmodynamic and hemodynamics situations were improved.The degrees of lung injury were relieved.Conclusion CMV can significantly improve hypoxemia of PE-SWD rabbits models.