| 先天性心脏病患儿弓形体感染的初步研究 |
| |
| 引用本文： | 侯晗,张国成,王晓明,许东亮,侯臣勋,郑跃杰,李飚. 先天性心脏病患儿弓形体感染的初步研究[J]. 临床儿科杂志, 2000, 18(3): 131-132 |
| |
| 作者姓名： | 侯晗 张国成 王晓明 许东亮 侯臣勋 郑跃杰 李飚 |
| |
| 作者单位： | 1. 第四军医大学西京医院儿科,710032
2. 山东省荷泽市第二人民医院 |
| |
| 摘 要： | 为探讨先心病（ＣＨＤ）与弓形体（ＴＯＸ）感染的关系，采用ＥＬＩＳＡ、ＰＣＲ技术分别检测ＣＨＤ患儿血清、心肌体及ＤＮＡ。结果：ＴＯＸ＿ＩｇＧ 阳性率在ＣＨＤ组和对照组之间差异有显著性；而ＴＯＸ－ＩｇＭ阳性率在两组之间差异无显著性。在ＴＯＸ－Ｉｂ3
|
| 关 键 词： | 先天性心脏病 弓形体感染 儿童 相互关系 |
| 修稿时间： | 1999-01-08 |
Preliminary study of toxoplasma gondii infection in children with congenital heart disease |
| |
| Hou Han,Zhang Guocheng,Wang Xiaoming,Xu Dongliang,Hou Chengxun,Zheng Yuejie,Li Biao. Preliminary study of toxoplasma gondii infection in children with congenital heart disease[J]. The Journal of Clinical Pediatrics, 2000, 18(3): 131-132 |
| |
| Authors: | Hou Han Zhang Guocheng Wang Xiaoming Xu Dongliang Hou Chengxun Zheng Yuejie Li Biao |
| |
| Affiliation: | Hou Han ,Zhang Guocheng ,WangXiaoming ,Xu Dongliang , Hou Chengxun ,Zheng Yuejie ;(The Department of Pediatrics, Xijing Hospital affiliated to the Fourth Military MedicalUniversity,Xian 710052) |
| |
| Abstract: | To explore the relationship of toxoplasma gondii(TOX) infection with congenital heart disease (CHD), serum TOX-IgG, TOX-IgM were detected in 37 CHD cases and 30 normal children by ELISA. TOX-DNA taken from the cardiac tissue was advanced investigated by polymerase chain reaction (PCR) in 20 cases who were confirmed with positive serum TOX-IgG. The results showed that there was a significant difference in the positive rate of TOX-IgG between two groups (x2 = 5. 284, P<0. 05). No significant difference in the positive rate of TOX-IgM was observed in two groups (x2 = 0. 06, P>0. 05). The positive rate of TOX-DNA from the cardiac tissue reached to 35% in the CHD cases who were with positive serum TOX-IgG. It is suggested that TOX infection be closely correlated with CHD as a teratogenic factor. |
| |
| Keywords: | congenital heart disease (CHD) toxoplasma gondii infection |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
