| 170例药物性肝损害的临床分析 |
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| 引用本文： | 杜建霞,沈玲.170例药物性肝损害的临床分析[J].中国药房,2008,19(2):138-139. |
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| 作者姓名： | 杜建霞 沈玲 |
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| 作者单位： | 东南大学医学院第二附属医院,南京市,210003 |
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| 摘 要： | 目的:探讨药物性肝损害的临床特点及其发生规律。方法:对我院2002年1月～2006年4月170例药物性肝损害患者的临床资料进行回顾性分析。结果:引起肝损害的药物中中草药占35.29%,抗精神病药占13.53%,抗结核药占12.94%;肝细胞损伤型占51.18%,胆汁淤积型占14.12%,混合型占34.71%。结论:药物性肝损害的临床特点与病毒性肝炎相似,并无特异性,引起肝损害的药物较多,应引起重视。
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| 关 键 词： | 药物性肝损害 回顾性分析 临床特点 |
| 文章编号： | 1001-0408(2008)02-0138-02 |
| 修稿时间： | 2007年10月8日 |
Drug-induced Hepatic Lesions:Clinical Analysis of 170 Cases |
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| DU Jian-xia,SHEN Ling.Drug-induced Hepatic Lesions:Clinical Analysis of 170 Cases[J].China Pharmacy,2008,19(2):138-139. |
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| Authors: | DU Jian-xia SHEN Ling |
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| Institution: | (The Second Affiliated Hospital of Medical College, Southeast University, Nanjing 210003, China) |
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| Abstract: | OBJECTIVE:To discuss the clinical features and the general pattern of drug-induced hepatic lesions.METHO-DS:The clinical data of 170 drug-induced hepatic lesion cases collected from Jan.2002 to Apr.2006 in our hospital were analyzed retrospectively.RESULTS:Of the 170 cases,35.29% were induced by Chinese herbal medicines,13.53% by antipsychotic drugs,12.94% by anti-tuberculosis agent;51.18% were hepatocellular damage type,14.12% cholestatic damage type and 34.71% damage of mixed type damage.CONCLUSION:Hepatic lesions resemble viral hepatitis and were of no specificity in clinical features;various drugs can lead to hepatic lesions and to which clinic should attach great importance. |
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| Keywords: | Drug-induced hepatic lesions Retrospective analysis Clinical feature |
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