| 雌二醇对离体大鼠缺氧─复氧心脏的保护作用 |
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| 引用本文： | 方廉,吴印生,陈少如,彭景添. 雌二醇对离体大鼠缺氧─复氧心脏的保护作用[J]. 中国病理生理杂志, 1994, 0(4) |
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| 作者姓名： | 方廉 吴印生 陈少如 彭景添 |
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| 作者单位： | 汕头大学医学院，江西医学院一附院心内科 |
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| 摘 要： | 本实验采用离体大鼠心脏灌注模型，观察雌二醇（３．３ｎｇ／ｍｌ）对缺氧─复氧心脏收缩功能及超微结构的影响。结果表明，雌二醇对缺氧─复氧心肌具有一定的保护作用，这一作用与雌激素能相对提高缺氧─复氧心肌组织中谷胱甘肽过氧化物酶（ＧＳＨ－Ｐｘ）活性和相对降低其Ｃａ￣（２＋）含量有关。
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| 关 键 词： | 大鼠；雌二醇；氧；游离基类 |
Protective effect of estradiol on isolated reperfused rat heart |
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| Fang Lian,Wu Yin-Sheng,et al. Protective effect of estradiol on isolated reperfused rat heart[J]. Chinese Journal of Pathophysiology, 1994, 0(4) |
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| Authors: | Fang Lian Wu Yin-Sheng et al |
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| Affiliation: | Fang Lian,Wu Yin-Sheng,et al Department of Physiology,Shantou University Medical College Shantou |
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| Abstract: | Protective effect of estradiol(3.3ng/ml)on isolated reperfused rat heartwas observed. The results suggested that estradiol has some protective effect on isolated ratheart from reperfusion injury which was related to relatively increased activity of GSH-Pxand relatively decreased calcium in myocardium. |
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| Keywords: | Rats Estradiol Oxygen Free radicals |
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