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Extramedullary granulopoiesis mimicking recurrent lymphoma after prolonged administration of human recombinant granulocyte colony-stimulating factor |
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| Authors: | H. D. Friedman S. O. Sanderson C. K. Stein A. Shrimpton N. J. Gonchoroff K. W. Zamkoff T. P. Loughran Jr. |
| Affiliation: | (1) Pathology and Laboratory Medicine, Service 113, VA Healthcare Network Upstate NY at Syracuse, 800 Irving Ave, Syracuse, NY 13210-2796, USA , US;(2) Department of Pathology, SUNY Health Science Center, Syracuse, NY 13210, USA, US;(3) Bone Marrow Transplantation, SUNY Health Science Center, Syracuse, NY 13210, USA, US;(4) Hematologic Malignancies, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612, USA, ML |
| Abstract: | Human recombinant granulocyte colony-stimulating factor (G-CSF) has become a treatment of choice for neutropenia of diverse etiologies. We describe a 71-year-old man who, while receiving G-CSF for graft failure after peripheral blood stem cell transplant, developed dramatic extramedullary granulopoiesis that mimicked recurrent lymphoma. Received: February 20, 1998 · Accepted: April 15, 1998 |
| Keywords: | G-CSF Peripheral blood stem cell transplantation Malignant lymphoma Extramedullary hematopoiesis FISH PCR-gene rearrangement |
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