| 异常黑素小体在恶性黑素瘤诊断中的意义 |
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| 引用本文： | 高天文 叶庆俏. 异常黑素小体在恶性黑素瘤诊断中的意义[J]. 第三军医大学学报, 1992, 14(4): 323-326 |
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| 作者姓名： | 高天文 叶庆俏 |
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| 作者单位： | 第三军医大学西南医院皮肤科 630038(高天文，叶庆俏)，第三军医大学西南医院皮肤科 630038(刘荣卿) |
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| 摘 要： | 应用透射电镜对17例恶性黑素瘤(MM)进行观察,并以30例色素痣作对照,重点探讨异常黑素小体在MM诊断中的价值。14例MM包括2例无色素性MM中找到异常黑素小体,2例含色素及1例无色素性MM中未找到异常黑素小体;4例先天性痣中发现异常黑素小体。结果提示:异常黑素小体对MM的诊断有重要参考价值,但以往对其意义估价过高,作者认为MM的透射电镜诊断需结合其它超微结构改变综合判断。
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| 关 键 词： | 超微结构 痣 黑色素瘤 恶性肿瘤 |
Significance of aberrant melanosomes in the diagnosis of malignant melanoma |
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| Gao Tianwen,Ye Qingyi,Liu Rongqing. Significance of aberrant melanosomes in the diagnosis of malignant melanoma[J]. Acta Academiae Medicinae Militaris Tertiae, 1992, 14(4): 323-326 |
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| Authors: | Gao Tianwen Ye Qingyi Liu Rongqing |
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| Abstract: | Seventeen cases of malignant melanoma (MM) were observed with transmission electron microscopy in order to clarify the significance of abberant melanosomes in its diagnosis.30 cases of nevus were also studied to serve as control.It was found that aberrant melanosomes were present in 14 cases of MM including 2 cases of amelanotic MM and absent in 2 cases of pigmented MM and one case of amelanotic MM.In addition,aberrant melanosomes were found in 4 cases of congenital nevus.The findings suggest that the significance of aberrant melanosomes in the diagnosis of MM has been overemphasized.It is believed that the diagnosis of MM must be judged comprehensively on all the ultrastructural changes under transmission electron microscope. |
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| Keywords: | melanoma/UL melanocytes nevus pigmented |
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