| 骨组织工程生物活性支架研究进展 |
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| 引用本文： | 吴王喜,周磊. 骨组织工程生物活性支架研究进展[J]. 中华创伤骨科杂志, 2006, 8(2): 165-168 |
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| 作者姓名： | 吴王喜 周磊 |
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| 作者单位： | 510280 广州,广东省口腔医院(南方医科大学附属口腔医院) |
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| 基金项目： | 广东省自然科学基金(2003-32569)~~ |
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| 摘 要： | 新型支架材料的研究趋势呈单一组分向多组分过渡,惰性材料向活性材料过渡,宏观水平向微观水平过渡。随着纳米技术与生命科学的迅猛发展,纳米改性与仿生构建这两个新理念也逐渐融入了支架研究的主流,网络成骨理论近年也在支架领域得到很好的拓展与应用。如何在原有研究的基础上研获理想的生物活性支架,已成为骨组织工程这一重大课题的核心热点和难点。本文重点探讨了骨组织工程中极具前景的几类生物支架,对其国内外研究与临床应用的现状做一综述。
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| 关 键 词： | 支架 骨组织工程 生物活性 细胞外基质 |
| 收稿时间： | 2005-12-14 |
| 修稿时间： | 2005-12-14 |
Progress in research and application of bioactive scaffolds in bone tissue engineering |
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| WU Wang-xi,ZHOU Lei. Progress in research and application of bioactive scaffolds in bone tissue engineering[J]. Chinese Journal of Orthopaedic Trauma, 2006, 8(2): 165-168 |
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| Authors: | WU Wang-xi ZHOU Lei |
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| Affiliation: | Guangdong Provincial Stomatological Hospital, Guangzhou 510280, China |
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| Abstract: | The research on novel scaffold materials is now characterized by a transition from single element to composition, from inert materials to bioactive materials, and from macro- level to micro- level. With the rapid development of nano- technology and life sciences, the two concepts of nano- modification and biomimic construction joined the mainstream of the scaffold research. And in this field, the theory of bone generation net has been recently explored systematically and comprehensively. As a result, it has now become a research focus to obtain ideal bioactive scaffolds on the basis of current investigation. This paper highlights several types of promising scaffolds, discusses their recent research and application, and reviews the present situation concerning bioactive scaffolds |
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| Keywords: | Scaffold Bone tissue engineering Bioactive Extracellular matrix |
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