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Discrimination between cases of duodenal ulcer and gastritis on the basis of putative virulence factors of Helicobacter pylori
Authors:Yamaoka Yoshio  Souchek Julianne  Odenbreit Stefan  Haas Rainer  Arnqvist Anna  Borén Thomas  Kodama Tadashi  Osato Michael S  Gutierrez Oscar  Kim Jong G  Graham David Y
Affiliation:Department of Medicine. Department of Health Services Research, Baylor College of MedicineVeterans Affairs Medical Center, Houston, Texas 77030, USA. yyamaoka@bcm.tmc.edu
Abstract:The BabA, cagA, and vacA statuses of 827 Helicobacter pylori isolates were used in logistic regression models to discriminate duodenal ulcer from gastritis. Only BabA was a candidate for a universal virulence factor, but the low c statistic value (0.581) indicates that none of these factors were helpful in predicting the clinical presentation.
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