Discrimination between cases of duodenal ulcer and gastritis on the basis of putative virulence factors of Helicobacter pylori |
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Authors: | Yamaoka Yoshio Souchek Julianne Odenbreit Stefan Haas Rainer Arnqvist Anna Borén Thomas Kodama Tadashi Osato Michael S Gutierrez Oscar Kim Jong G Graham David Y |
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Affiliation: | Department of Medicine. Department of Health Services Research, Baylor College of MedicineVeterans Affairs Medical Center, Houston, Texas 77030, USA. yyamaoka@bcm.tmc.edu |
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Abstract: | The BabA, cagA, and vacA statuses of 827 Helicobacter pylori isolates were used in logistic regression models to discriminate duodenal ulcer from gastritis. Only BabA was a candidate for a universal virulence factor, but the low c statistic value (0.581) indicates that none of these factors were helpful in predicting the clinical presentation. |
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