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微柱凝胶技术用于新生儿溶血病诊断的效果评价
引用本文:廖长征,黄衍锋,许瑞环,叶有玩.微柱凝胶技术用于新生儿溶血病诊断的效果评价[J].中国热带医学,2007,7(3):436-437.
作者姓名:廖长征  黄衍锋  许瑞环  叶有玩
作者单位:深圳市龙岗中心医院,广东,深圳,518116
摘    要:目的探讨微柱凝胶技术(MCCT)在新生儿溶血病(HDN)中的诊断效果。方法采用MCCT对105例HDN患儿进行检测试验:直接抗球蛋白试验;游离IgG抗体试验;放散试验。同时用传统的试管法抗球蛋白试验(TCT)作比较。结果统计学上两种方法对HDN检出率无显著性差别,但MGCT能检出TCT所不能检出的阴性血样,比TCT检测凝集强度高1+ ~2+。结论MGCT能快速准确检测出HDN,具有更高的灵敏度,操作简便,结果可保存。

关 键 词:微柱凝集技术  新生儿溶血病  抗人球蛋白试验
文章编号:1009-9727(2007)3-436-02
收稿时间:2006-12-11
修稿时间:2006年12月11

Observation on the results of application of microcolumn gel technique in diagnosis of neonatal hemolytic disease in the newborns
LIAO Chang- zheng, HUANG Yah- feng, XU Rui- huan,et al..Observation on the results of application of microcolumn gel technique in diagnosis of neonatal hemolytic disease in the newborns[J].China Tropical Medicine,2007,7(3):436-437.
Authors:LIAO Chang- zheng  HUANG Yah- feng  XU Rui- huan  
Institution:LIAO Chang- zheng, HUANG Yah- feng, XU Rui- huan, et al.
Abstract:Objective To discuss the results of micro column gel coombs(MGCT) in diagnosis of hemolytic disease of newborn (HDN). Methods 105 patients with HDN were tested by MGCT, including direct anti-human globulin test with MGCT, free IgG antibody test and eluting test. The results were compared with traditional TCT anti human IgG test. Results There no significant differences were observed in the rates of detection of HDN between the two methods. Negative samples could be detected by MGCT that could not be detected by TCT. Conclusion MGCT is sensitive, simple and accurate in detection of HDN.
Keywords:Hemolytic disease of newborn  Anti - human globulin test  Micro column gel coombs test
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