结直肠癌肝转移相关的病理组织学评价

 目的　探讨结直肠癌肝转移的病理组织学特性。方法　对 335例行结直肠癌切除的患者行回顾性病理组织学研究 ,将有肝转移者的病理组织学参数与无肝转移者对比。结果　本组 4 1例 (12 % )有肝转移 ,有肝转移者与无肝转移者诸因素的百分率比较为 :肿瘤大小超过 6cm(5 1%υs 2 8% ;P <0 .0 1) ,肠系膜浸润 (98%υs 6 6 % ;P <0 .0 1) ,淋巴结浸润 (34%υs 15 % ;P <0 .0 1) ,静脉浸润 (2 4 %υs 3% ;P <0 .0 1) ,和淋巴结转移 (85 %υs 39% ;P <0 .0 1)。多元回归分析显示 :与肝转移有关的独立因素是肠系膜浸润、静脉浸润和淋巴结转移。诊断肝转移的精确度最高的是静脉浸润 (88% ) ,最低的是肠系膜浸润(41% )。在 98例有肠系膜和淋巴结转移者中 ,有肝转移者与无肝转移者静脉浸润差异非常显著 (2 6 %υs 6 % ;P <0 .0 1) ,其肠外淋巴结转移差异显著 (6 8%υs 4 7% ;P <0 .0 5 )。结论　结直肠癌肝转移的重要因素是肠系膜浸润 ,静脉浸润和淋巴结转移。其决定因素是静脉...

Relative Histopathologic Evaluation of Colorectal Cancer with Liver Metastasis

Objective To study the histopathologic characteristics of colorectal cancer with liver metastasis.Methods We performed a retrospective histopathologic study on 335 patients who underwent resection of colorectal cancer. Histopathologic parameters of tumors with liver metastasis.Results Forty-one patients (12 percent) had liver metastasis. Tumors having liver metastasis, when compared with those not having live metastasis,were characterized by high frequency of tumor size more than 6 cm (51υs 28 percent; ...