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苦楝皮化学成分研究
引用本文:刘少超,白虹,唐文照,马腾,姚庆强. 苦楝皮化学成分研究[J]. 中国实验方剂学杂志, 2011, 17(6): 93-96
作者姓名:刘少超  白虹  唐文照  马腾  姚庆强
作者单位:山东省医学科学院药物研究所,山东省罕少见病重点实验室,济南,250062
摘    要:目的:研究苦楝皮Melia azedarach L.的化学成分。方法:采用硅胶柱色谱技术分离纯化,通过光谱学方法鉴定化合物的结构。结果:分离并鉴定出7个化合物,分别为4,8-二羟基-1-四氢萘醌(isosclerone,Ⅰ),梣酮(fraxinellone,Ⅱ),苦楝皮萜酮(kulinone,Ⅲ),苦楝萜酮内酯(kulactone,Ⅳ),南岭楝酮B(dubione B,Ⅴ),苦楝酸(kulonic acid,Ⅵ)和β-谷甾醇(β-sitosterol,Ⅶ),丁二酸(succinic,Ⅷ),5-(羟甲基)-2-呋喃甲醛[5-(hydroxymethyl)-2-furaldehyde,Ⅸ]。结论:化合物Ⅰ,Ⅷ和Ⅸ系首次从该植物中分得。

关 键 词:苦楝皮  化学成分  结构鉴定
收稿时间:2010-11-16

Study on Chemical Constituents of Melia azedarach
LIU Shao-chao,BAI Hong,TANG Wen-zhao,MA Teng and YAO Qing-qiang. Study on Chemical Constituents of Melia azedarach[J]. China Journal of Experimental Traditional Medical Formulae, 2011, 17(6): 93-96
Authors:LIU Shao-chao  BAI Hong  TANG Wen-zhao  MA Teng  YAO Qing-qiang
Affiliation:Key Laboratory of Rare and Uncommon Disease of Shandong Province, Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan 250062, China;Key Laboratory of Rare and Uncommon Disease of Shandong Province, Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan 250062, China;Key Laboratory of Rare and Uncommon Disease of Shandong Province, Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan 250062, China;Key Laboratory of Rare and Uncommon Disease of Shandong Province, Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan 250062, China;Key Laboratory of Rare and Uncommon Disease of Shandong Province, Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan 250062, China
Abstract:
Keywords:Melia azedarach   chemical constituents  structural identification
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