| 卡维地洛对慢性心衰患者糖、脂代谢的影响 |
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| 引用本文： | 傅文中,洪中立,马苏亚,陈国英. 卡维地洛对慢性心衰患者糖、脂代谢的影响[J]. 心脑血管病防治, 2006, 6(5): 292-293 |
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| 作者姓名： | 傅文中 洪中立 马苏亚 陈国英 |
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| 作者单位： | 1. 宁波市镇海龙赛医院,浙江,宁波,315200
2. 宁波大学医学院附属医院,宁波,315010 |
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| 摘 要： | 目的观察卡维地洛对慢性心衰患者的疗效及其对血糖,血脂代谢的影响。方法入选CHF患者59例,随机分为对照组:应用常规抗CHF治疗组(30例)和卡维地洛组(29例),后者在常规抗CHF治疗基础上加用卡维地洛,疗程为24周,治疗前后均测定左室舒张末期内径(LVDd)和收缩末期内径(LVDs)、左室射血分数(LVEF)、空腹血糖(FBS)、糖化血红蛋白(HbAlc)、血脂。结果卡维地洛组改善LVDd、LVDs和LVEF均优于常规抗CHF治疗组(P<0.01),治疗后卡维地络组TC、LDL-C较对照组降低(P<0.05)。结论卡维地洛可有效改善CHF患者的心功能,对糖、脂代谢有一定的益处。
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| 关 键 词： | 卡维地洛 慢性心力衰竭 糖 脂代谢 |
| 文章编号： | 1009-816X（2006）05-0292-02 |
| 收稿时间： | 2006-07-15 |
| 修稿时间： | 2006-08-30 |
Effects of Carvedilol on Glucose and Lipid Metablism in Patients with Chronic Heart Failure |
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| FU Wen-zhong, HONG Zhong-li, MA Su-ya, et all.. Effects of Carvedilol on Glucose and Lipid Metablism in Patients with Chronic Heart Failure[J]. Prevention and Treatment of Cardio_Cerebral_Vascular Disease, 2006, 6(5): 292-293 |
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| Authors: | FU Wen-zhong HONG Zhong-li MA Su-ya et all. |
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| Abstract: | Objective To investigate the effects of carvedilol on glucose and lipid metabolism in patients with chronic heart failure(CHF).Methods Fifty nine patients with CHF were divided randomly into CHF treatment group(30 cases) and carvedilol treatment group(29 cases).LVDd,LVDs,LVEF,FBS,HbAIc,TC,TG,LDLC and HDL-C were detected before and after 24 week's treatment.Results Compared with CHF treatment group,LVEF was significantly increased(39.6±4.5% Vs 36.3±5.0%,P<0.01),and LVDd,LVDs were significantly decreased in carvedilol treatment group(55.2±5.9 Vs 62.6±5.7,45.6±6.4 Vs 53.2±5.6,respectively;P<0.01). TC,LDL-C in carvedilol treatment group were significantly decreased(5.22±0.6 Vs 5.88±0.89;3.4±0.8 Vs 4.0±0.9;P<0.05).Conclusions Carvedilol could improve cardiac function and had benefit for glucose and lipid metabolism. |
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| Keywords: | Carvedilol Chronic heart failure Glucose Lipid metabolism |
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