| 糖耐量减低者血清抵抗素水平的变化及二甲双胍对其水平的影响 |
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| 引用本文： | 李晓岚,罗荔,王敏哲.糖耐量减低者血清抵抗素水平的变化及二甲双胍对其水平的影响[J].新疆医科大学学报,2012,35(8):1035-1037. |
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| 作者姓名： | 李晓岚 罗荔 王敏哲 |
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| 作者单位： | 新疆医科大学第五附属医院内分泌科,乌鲁木齐,830011 |
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| 基金项目： | 新疆维吾尔自治区自然科学基金 |
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| 摘 要： | 目的探讨糖耐量减低(IGT)患者血清抵抗素(Res)水平的变化及二甲双胍干预对糖耐量减低患者Res水平的影响。方法分别测定156例糖耐量减低患者(IGT组)和150例糖耐量正常者(CG组)的空腹Res水平,并进行组间比较,二甲双胍干预IGT组3个月后,进行干预前后自身比较,分析二甲双胍对Res的影响。结果 IGT组Res水平显著高于CG组(P<0.05);IGT组经二甲双胍干预后,Res水平较干预前有所下降(P<0.05)。结论 IGT患者Res水平高于CG者,二甲双胍治疗可以降低IGT者的Res水平,改善胰岛素抵抗。
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| 关 键 词： | 糖耐量减低 抵抗素 二甲双胍 |
Serum resistin level of impaired glucose tolerance patients and effect of metformin on its level |
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| LI Xiao-lan
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LUO Li
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WANG Min-zhe.Serum resistin level of impaired glucose tolerance patients and effect of metformin on its level[J].Journal of Xinjiang Medical University,2012,35(8):1035-1037. |
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| Authors: | LI Xiao-lan LUO Li WANG Min-zhe |
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| Institution: | (Department of Endocrinology,The Fifth Hospital,Xinjiang Medical University, Urumqi 830011,China) |
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| Abstract: | Obective To analyze the serum resistin level of impaired glucose tolerance patients(IGT) and effect of metformin on it.Methods The first stage,the fasting serum level of resistin was examined in 156 patients with IGT and 150 person with normal glucose tolerance(NGT),and the results was compared in different groups.Second stage,Patients with IGT were cured by metformin 3 months persistly,and to analyze the effect of metformin.Results The fasting serum resistin concentrations was significantly higher in IGT than in NGT groups(P<0.05).The fasting serum resistin concentrations was significantly lower after metformin′s treatment(P<0.05).Conclusion IGT′s serum resistin concentrations was higher than NGT and metformin’s treatment can decrease the fasting serum resistin concentrations of IGT. |
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| Keywords: | pre-diabetes resistin correlated factor |
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