妊娠期常规行宫颈疾病筛查可行性及结果分析

目的通过对妊娠期宫颈疾病筛查结果的分析，探讨对妊娠期常规进行宫颈疾病筛查的必要性。方法2007年3月1日至2008年5月31日在我院正规接受产前检查的孕妇共2 338例，所有孕妇均在首次产前检查时采用TCT技术常规行宫颈细胞学检查，对细胞学检查异常的孕妇进行人乳头瘤病毒检测及宫颈活检。结果2 338例孕妇中细胞学检查异常者43例，占1.84%，其中ASCUS 27例，LSIL14例，HSIL2例。宫颈活检结果慢性宫颈炎14例，CINⅠ11例，CINⅡ9例，CINⅢ9例。高危HPV检测阳性36例，占83.72%。除1例因合并梅毒要求引产外其余均足月分娩。结论产前检查时应进行宫颈疾病筛查有助于及时发现宫颈疾病，细胞学筛查及宫颈活检对孕妇是安全、可行、必要的。

Feasibility and result of routine screening for cervical disease during gestational period

Objective To discuss the necessity of conventional cervical diseases screening for pregnant women during gestational period by analyzing the results of cervical screening. Methods Two thousand three hundred and thirty-eight pregnant women who received regular prenatal care were accepted conventional cervical cytology test in prenatal care for the first time in our hospital from March 1, 2007 to May 31, 2008. The patients with abnormal cytology screen accepted the test of HPV test and cervical biopsy. Results In 2 338 cases, there were 43 （ 1. 84% ） pregnant women with abnormal cytology test result, 27 cases with atypical squamous cell of undetermined signification （ASCUS）, 14 cases with low-grade intraepithelial lesions （LSIL）, 2 cases with high-grade intraepithelial lesions （HSIL）. Cervical biopsy indicated 14 cases with chronic cervicitis, 11 cases with cervical intraepithelial neoplasia （CIN Ⅰ ）, 9 cases with CIN Ⅱ,9 cases with CINⅢ. There were 36 cases （83.72%） with high risk of human papillomavirus （HPV）. Among the pregnant cases, forty-two cases delivered at full term, with one induced labor due to syphilis. Conclusion Prenatal screening for cervical diseases screening could help to detect cervical diseases, cervical cytology screening and biopsy for pregnant women are safe, feasible and necessary.