| 白细胞介素-1单核苷酸多态性与甘肃回族、东乡族人群慢性牙周炎的相关性研究 |
| |
| 引用本文： | Yang L,Xie X,Ma L,Liu Z,Pan Y,Liu Y. 白细胞介素-1单核苷酸多态性与甘肃回族、东乡族人群慢性牙周炎的相关性研究[J]. 华西口腔医学杂志, 2011, 29(4): 365-368. DOI: 10.3969/j.issn.1000-1182.2011.04.008 |
| |
| 作者姓名： | Yang L Xie X Ma L Liu Z Pan Y Liu Y |
| |
| 作者单位： | 1.兰州大学第二医院口腔科, 兰州730030; 2.兰州大学基础医学院遗传学研究所, 兰州730000;3.西北民族大学医学院口腔教研室, 兰州730030; 4.临夏州人民医院口腔科, 临夏731200;5.临夏州广河县人民医院口腔科, 临夏731203 |
| |
| 基金项目： | 甘肃省科技攻关基金资助项目(2GS064-A43-020-10) |
| |
| 摘 要： | 目的 通过检测并分析白细胞介素(IL)-1B+3954位点的单核苷酸多态性(SNP),探索其与甘肃回族与东乡族人群慢性牙周炎的关系.方法 收集215例回族、东乡族慢性牙周炎患者及219例正常对照组健康者的静脉血,提取外周静脉血白细胞DNA,采用聚合酶链式反应-限制性片段长度多态性技术(PCR-RFLP)方法检测IL-1...
|
| 关 键 词： | 慢性牙周炎 白细胞介素-1 单核苷酸多态性 |
| 收稿时间： | 2011-08-25 |
| 修稿时间： | 2011-08-25 |
A study of association between the interleukin-1 single nucleotide polymorphism and risk of chronic periodontitis among the Hui and Dongxiang minorities in Gansu province |
| |
| Yang Lan,Xie Xiaodong,Ma Liyang,Liu Zhishou,Pan Yulan,Liu Yanbin. A study of association between the interleukin-1 single nucleotide polymorphism and risk of chronic periodontitis among the Hui and Dongxiang minorities in Gansu province[J]. West China journal of stomatology, 2011, 29(4): 365-368. DOI: 10.3969/j.issn.1000-1182.2011.04.008 |
| |
| Authors: | Yang Lan Xie Xiaodong Ma Liyang Liu Zhishou Pan Yulan Liu Yanbin |
| |
| Affiliation: | 1. Dept. of Stomatology, Second Hospital of Lanzhou University, Lanzhou 730030, China; 2. Institute of Genetics, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China; 3. Dept. of Dentistry, Medical College of Northwest University for Nationalities, Lanzhou 730030, China; 4. Dept. of Stomatology, People’s Hospital of Linxia, Linxia 731200, China; 5. Dept. of Stomatology, People’s Hospital of Guanghe County, Linxia 731203, China |
| |
| Abstract: | Objective To examine and analyze the interleukin(IL)-1B gene single nucleotide polymorphism(SNP) at positions +3954,and explore the association between SNP and risk of chronic periodontitis(CP) among the Hui and Dongxiang minorities in Gansu province.Methods CP group consisted of 215 patients from Hui and Dongxiang and healthy control group consisted of 219 subjects.Anti-coagulated peripheral blood sample was obtained from each subject and genomic DNA was extracted from each sample.SNP at IL-1B+3954 were an... |
| |
| Keywords: | chronic periodontitis interleukin-1 single nucleotide polymorphism |
| 本文献已被 CNKI 万方数据 PubMed 等数据库收录！ |
| 点击此处可从《华西口腔医学杂志》浏览原始摘要信息 |
|
点击此处可从《华西口腔医学杂志》下载免费的PDF全文 |
|
