上海市松江区佘山镇老年人痴呆患病率调查

目的:调查上海市松江区佘山镇60岁及以上老年人的痴呆患病现状。方法:在上海市松江区的佘山镇采用横断面研究,对当地60岁及以上常住居民的痴呆患病率进行调查。以中文版简易智能状态检查量表(C-MMSE)筛查认知功能障碍,并进一步由神经科医师通过相关神经科检查及有关量表测试,参照最新推荐的国际诊断标准确定痴呆及其分型的诊断。结果:此次研究顺利完成C-MMSE初筛的研究对象共有1 472例,占有资格参加本研究总人数的71.7%;其中男666例,女806例。研究对象中被确认为认知功能障碍者167例(11.3%)。诊断为痴呆者79例,患病率为5.4%95%可信区间(CI):4.8%～6.0%],其中诊断为阿尔茨海默病(AD)者56例(男16例,女40例),患病率为3.8%(95%CI:3.3%～4.3%),诊断为血管性痴呆(VaD)者18例(男5例,女13例),患病率为1.2%(95%CI:0.9%～1.5%)。结论:上海市松江区佘山镇老年人痴呆和AD患病率较高。

Prevalence of dementia among elderly people in Sheshan town, Songjiang district, Shanghai

Objective To investigate the prevalence of dementia among elderly people aged 60 years and over in Sheshan town,Songjiang district,Shanghai.Methods A cross-sectional study of prevalence of dementia was conducted in Sheshan town of Songjiang district,located in the south-west suburb of Shanghai.Residents aged 60 years and over were eligible to participate in the study.The Chinese version of the mini-mental status examination(C-MMSE) was used to screen subjects with cognitive impairment.The diagnosis of dementia and its subtypes was validated by senior neurologists according to the recently recommended diagnostic criteria.Results There were 1 472 subjects(666 males and 806 females) who completed the interview and C-MMSE,accounting for 71.7% of all eligible subjects.Cognitive impairment was recognized in 167 subjects,and dementia was diagnosed in 79 subjects with a prevalence rate of 5.4%(95% CI: 4.8%-6.0%).The diagnosis of Alzheimer disease(AD) was validated in 56 subjects(16 males and 40 females) with a prevalence rate of 3.8%(95% CI: 3.3%-4.3%),and vascular dementia(VaD) was diagnosed in 18 subjects(5 males and 13 females) with a prevalence rate of 1.2%(95% CI: 0.9%-1.5%).Conclusions The prevalence of dementia and AD among elderly people is high in Sheshan town,Songjiang district,Shanghai.