| 肾素-血管紧张素系统与支气管哮喘 |
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| 引用本文： | 常绍鸿,栾斌.肾素-血管紧张素系统与支气管哮喘[J].国际呼吸杂志,2008,28(7):403-405. |
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| 作者姓名： | 常绍鸿 栾斌 |
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| 作者单位： | 郑州大学第三附属医院儿科,450000 |
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| 摘 要： | 支气管哮喘(哮喘)是全球范围内严重威胁公众健康的慢性疾病之一,是以气道慢性炎症和气道重塑为基本病理特征的慢性疾病.近年来,大量研究显示肾素一血管紧张素系统(renin-angiotensin system,RAS)参与了哮喘的急性发作和气道重塑过程.因此,应用血管紧张素转换酶抑制剂和血管紧张素受体阻断剂治疗和预防哮喘发作,可望成为哮喘治疗的一个重要方法.本文综述了RAS在哮喘发生、发展过程中的作用.
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| 关 键 词： | 支气管哮喘 肾素-血管紧张素系统 血管紧张素Ⅱ |
Role of renin-angiotensin system in bronchial asthma |
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| CHANG Shao-hong,LUAN Bin.Role of renin-angiotensin system in bronchial asthma[J].International Journal of Respiration,2008,28(7):403-405. |
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| Authors: | CHANG Shao-hong LUAN Bin |
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| Abstract: | Bronchial asthma is a chronic disease that seriously threatens human health all over the world.It is characterized by chronic inflammation and airway remodeling.Recent studies indicate that reninangiotensin system(RAS)is related to bronchial asthma.Therefore,using angiotensin-converting enzyme inhibitors or ARBs to inhibit RAS may be a important way for prevention and control of asthma.In this text,the role of RAS in asthma is introduced. |
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| Keywords: | Asthma Renin-angiotensin system Angiotensin Ⅱ |
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