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A case of colon cancer with multiple liver metastases effectively treated with hepatic arterial infusion followed by systemic chemotherapy
Authors:Yamauchi Shinichi  Uetake Hiroyuki  Miyazaki Koji  Kikuchi Akifumi  Ono Hiroaki  Kato Shunsuke  Ishiguro Megumi  Ishikawa Toshiaki  Kobayashi Hirotoshi  Iida Satoru  Higuchi Tetsuro  Enomoto Masayuki  Sugihara Kenichi
Affiliation:Dept. of Surgical Oncology, Tokyo Medical and Dental University Graduate School.
Abstract:A 63-year-old female was diagnosed as descending colon cancer with severe liver dysfunction caused by multiple liver metastases. Her performance status (PS) was 3 because of liver dysfunction and high fever. Initially, hepatic arterial infusion (HAI) chemotherapy was started to reduce the size of metastatic tumors and to prevent a liver failure. After 10 courses of HAI chemotherapy, she recovered from liver dysfunction, and CapeOX plus bevacizumab regimen was started. A partial response of metastatic liver tumors was observed after 8 cycles of this regimen and metastatic lung tumors were disappeared. The patient was alive after 12 months with PS 0 and CapeOX was continued.
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