| 伤疡愈凝胶的制备及质量标准研究 |
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| 引用本文： | 杨戒骄,谢东. 伤疡愈凝胶的制备及质量标准研究[J]. 中国药房, 2007, 18(9): 663-664 |
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| 作者姓名： | 杨戒骄 谢东 |
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| 作者单位： | 深圳市人民医院、暨南大学附属第二医院药学部,深圳市,518020 |
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| 基金项目： | 广东省深圳市科技局科研项目 |
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| 摘 要： | 目的:制备伤疡愈凝胶并建立其质量标准。方法:以卡波姆940为凝胶基质制备伤疡愈凝胶。采用分光光度法在516nm波长处测定其含量;其它成分用薄层色谱法进行鉴别。结果:左旋紫草素浓度在8.048～40.24μg.mL-1范围内线性关系良好(r=0.9998),平均回收率为99.45%(RSD=1.13%)。结论:本制剂制备工艺简便,所建标准可用于质量控制。
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| 关 键 词： | 伤疡愈凝胶 制备工艺 质量标准 分光光度法 薄层色谱法 |
| 文章编号： | 1001-0408(2007)09-0663-02 |
| 收稿时间： | 2006-06-22 |
| 修稿时间： | 2006-10-27 |
Study on Preparation and Quality Standard of Shangyangyu Gel |
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| YANG Jiejiao,XIE Dong. Study on Preparation and Quality Standard of Shangyangyu Gel[J]. China Pharmacy, 2007, 18(9): 663-664 |
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| Authors: | YANG Jiejiao XIE Dong |
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| Abstract: | OBJECTIVE:To prepare Shangyangyu gel and establish a standard for its quality.METHODS:Shangyangyu gel was prepared using carbamer 940 as matrix.Its content was identified by spectrophotography,with the wavelength set at 516nm,and its other compositions were determined by TLC.RESULTS:The concentration of L-shikonin had good linear correlation with absorbance in the range of 8.048～ 40.24μ g· mL-1(r=0.999 8).The average recovery rate was 99.45%(RSD=1.13%).CONCLUSION:This method for preparation of Shangyangyu gel was simple in technique and the standard can be used for the quality control. |
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| Keywords: | Shangyangyu gel Preparation process Quality control Spectrophotography TLC |
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