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陶瓷样异种骨对骨髓基质细胞生长及附着影响的实验研究
引用本文:李彦林,韩睿,李世和,曾才铭,王宏邦.陶瓷样异种骨对骨髓基质细胞生长及附着影响的实验研究[J].昆明医学院学报,2003,24(2):32-35.
作者姓名:李彦林  韩睿  李世和  曾才铭  王宏邦
作者单位:昆明医学院第一附属医院骨科,昆明,650032
基金项目:云南省应用基础研究基金资助项目 ( 2 0 0 0C0 0 10R)
摘    要:目的:探讨陶瓷样异种骨(CXB)与骨髓基质细胞的生物相容性,为CXB复合骨髓移植修复骨缺损提供依据.方法:将理化处理制得的陶瓷样异种骨(CXB)与兔骨髓基质细胞体外复合培养,用倒置相差显微镜及扫描电镜观察CXB对骨髓基质细胞的形态、生长、附着及增殖的影响.结果:CXB对骨髓基质细胞的形态、生长、附着及增殖均无不良影响,显示出良好的生物相容性.结论:CXB具有良好的生物相容性,可望与骨髓复合移植修复骨缺损.

关 键 词:陶瓷样异种骨  骨髓基质细胞  生长  附着  生物相容性  骨缺损  修复  骨移植
文章编号:1003-4706(2003)02-0032-04
修稿时间:2003年1月20日

Biocompatibility Studies on Ceramiclike Xenogeneic Bone with Bone Marrow Stromal Cells in Vitro
LI Yan-lin,HAN Rui,LI Shi-he,ZENG Cai-ming,WANG Hong-bang.Biocompatibility Studies on Ceramiclike Xenogeneic Bone with Bone Marrow Stromal Cells in Vitro[J].Journal of Kunming Medical College,2003,24(2):32-35.
Authors:LI Yan-lin  HAN Rui  LI Shi-he  ZENG Cai-ming  WANG Hong-bang
Abstract:Objective: To study the biocompatibility on Ceramiclike Xenogeneic Bone(CXB) with cultured bone marrow stromal cells(BMSCs). Methods: Bone marrow stromal cells were cultured with CXB in vitro, The affects on morphologic features,growth,attachment and proliferation of BMSCs were observed by phase microscope and electronic scanning microscope. Results: CXB had not any bad affects on the morphologic features,growth,attachment and proliferation of BMSCs, So CXB had good biocompatibility. Conclusion : CXB has good biocompatibility and it could be used to repair bone defects combined with bone marrow.
Keywords:Ceramiclike xenogeneic bone  Bone marrow stromal cells  Biocompatibility
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