Adaptation of the membrane receptor apparatus of blood cells after the combined use of cryodestruction and plasma beam in experimental cirrhosis of the liver

It is shown that cryodestruction combined with resection with a plasma beam aggravates alterations of the functions of the blood cell receptor complex affected by cirrhosis, leading to hypoinsulinemia, inhibited capacity of cells to utilize glucose, a lowered metabolic activity of insulin receptors, and other changes. Three weeks after surgery the energy metabolism of the blood cells returns to the normal level, while the activity of insulin receptors and of hexokinase exceeds the control level. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, N ^o 6, pp. 647–650, June, 1995 Presented by V. N. Yarygin, Member of the Russian Academy of Medical Sciences