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Variability of cognitive development in children with Down syndrome: Relevance of good reasons for using the cluster procedure
Authors:R Tsao  C Kindelberger
Institution:1. Human Development and Family Studies, Colorado State University, Fort Collins, CO, United States;2. Peabody College, Vanderbilt University, Nashville, TN, United States;3. Vanderbilt Kennedy Center''s University Center for Excellence in Developmental Disabilities, Nashville, TN, United States;1. Centre of National Research on Disability and Rehabilitation Medicine, The University of Queensland, Australia;2. Curtin Bankwest Economics Centre, Curtin University, Australia;3. School of Commerce, University of Southern Queensland, Australia;4. Australian Centre for Economic Research on Health, School of Economics and Centre for Clinical Research, The University of Queensland, Australia;5. School of Economics, The University of Queensland, Australia
Abstract:The main goal of this cross-sectional study was to demonstrate that, in addition to a main change during childhood, the cognitive development of children with Down syndrome (DS) is characterized by interindividual variability in their cognitive functioning. Eighty-eight French children with DS took part in this experiment. They were divided into six chronological age groups: 6 years (N = 9), 7 years (N = 19), 8 years (N = 18), 9 years (N = 19), 10 years (N = 14) and 11 years (N = 9). They were assessed by means of the Differential Scales of Intellectual Efficiency. This test, composed of six independent scales, measures verbal abilities and nonverbal reasoning abilities. Initial analyses of the verbal and nonverbal subtest scores indicated a main change in cognitive skills. We then used a clustering approach to identify four cognitive profiles that distinguished the children with DS independently of age and gender. The results confirm that there is a growth in the cognitive skills of DS children. They also suggest that the cognitive functioning of DS children is characterized by different individual profiles. Implications for more fine-tuned research and intervention efforts are discussed.
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