不同雾化吸入方式对老年泌尿外科全麻术后肺部并发症的影响研究

目的探讨不同雾化吸入方式对老年泌尿外科全身麻醉(全麻)术后肺部并发症的影响。方法125例老年泌尿外科全麻术后患者,随机分为观察组(63例)与对照组(62例)。两组雾化药物均采用氨溴索,对照组患者应用超声雾化,观察组患者应用氧气雾化。比较两组患者治疗前后血压、血氧饱和度、痰液粘弹性以及肺部并发症发生情况。结果治疗后,两组收缩压、舒张压均低于治疗前,血氧饱和度高于治疗前,且观察组患者收缩压(105.57±8.31)mm Hg(1 mm Hg=0.133 kPa)、舒张压(82.10±4.06)mm Hg均低于对照组的(134.03±10.52)、(85.13±4.44)mm Hg,血氧饱和度(95.06±3.40)%高于对照组的(90.40±3.31)%,差异均具有统计学意义(P<0.05)。两组患者痰液粘弹性均低于治疗前,且观察组患者痰液粘弹性(0.22±0.03)低于对照组的(0.61±0.33),差异均具有统计学意义(P<0.05)。观察组肺部并发症发生率4.8%低于对照组的16.1%,差异具有统计学意义(P<0.05)。结论氧气雾化与超声雾化盐酸氨溴索均能改善老年泌尿外科全麻术后患者呼吸道症状,氧气雾化方式患者氧饱和度升高显著,肺部并发症发生率低。

Effect of different nebulization modes on postoperative pulmonary complications of general anesthesia in elderly urology patients

Objective To discuss the effect of different nebulization modes on postoperative pulmonary complications of general anesthesia in elderly urology patients.Methods A total of 125 elderly patients after general anesthesia for urological surgery were randomly divided into observation group(63 cases)and control group(62 cases).The control group was treated with ultrasound nebulization of ambroxol,and the observation group was treated with oxygen-driven nebulization of ambroxol.The blood pressure,oxygen saturation,aputum viscoelasticity before and after treatment and occurrence of pulmonary complications were compared between the two groups.Results After treatment,the systolic blood pressure and diastolic blood pressure of the two groups were lower than those before treatment,and oxygen saturation was higher than that before treatment.The systolic blood pressure(105.57±8.31)mm Hg(1 mm Hg=0.133 kPa)and diastolic blood pressure(82.10±4.06)mm Hg of the observation group were lower than(134.03±10.52)and(85.13±4.44)mm Hg of the control group,and oxygen saturation(95.06±3.40)%was higher than(90.40±3.31)%of the control group.All the difference was statistically significant(P<0.05).The aputum viscoelasticity of the two groups was lower than that before treatment,and the observation group(0.22±0.03)was lower than(0.61±0.33)of the control group.All the difference was statistically significant(P<0.05).The incidence of pulmonary complications 4.8%of the observation group was lower than 16.1%of the control group,and the difference was statistically significant(P<0.05).Conclusion Both oxygen-driven nebulization and ultrasound nebulization of ambroxol can improve the respiratory symptoms in elderly patients after general anesthesia in urology department,and patients in the oxygen-driven nebulization have a significant increase in oxygen saturation and a low incidence of pulmonary complications.