| Furin在心血管系统发育和心血管疾病中的研究进展 |
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| 引用本文： | 施凯佳,阮班展,赵鋆,揭伟,郭峻莉.Furin在心血管系统发育和心血管疾病中的研究进展[J].中国动脉硬化杂志,2022,30(8):731-736. |
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| 作者姓名： | 施凯佳 阮班展 赵鋆 揭伟 郭峻莉 |
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| 作者单位： | 海南医学院第一附属医院海南省热带心血管病研究重点实验室,海南省海口市 571199;海南医学院第一附属医院海南省热带心血管病研究重点实验室,海南省海口市 571199;海南医学院急救与创伤研究教育部重点实验室 中国医学科学院海岛急救医学创新单元2019RU013,海南省海口市 571199 |
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| 基金项目： | 中国医学科学院医学与健康科技创新工程项目(2019-I2M-5-023) |
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| 摘 要： | 心血管系统发育与心血管疾病是极其复杂的过程。Furin是一种内切蛋白酶,参与心血管系统发育及心血管疾病的发生和发展过程,具有重要的生物学功能。本文主要综述了Furin在心血管系统发育中的作用,并探讨了Furin与心血管疾病的关系,为预防和治疗各种心血管疾病提供了新的靶点。
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| 关 键 词： | Furin 心血管系统发育 心血管疾病 |
| 收稿时间： | 2021/6/1 0:00:00 |
| 修稿时间： | 2021/12/9 0:00:00 |
Research progress of Furin in cardiovascular system development and cardiovascular diseases |
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| SHI Kaiji,RUAN Banzhan,ZHAO Yun,JIE Wei,GUO Junli.Research progress of Furin in cardiovascular system development and cardiovascular diseases[J].Chinese Journal of Arteriosclerosis,2022,30(8):731-736. |
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| Authors: | SHI Kaiji RUAN Banzhan ZHAO Yun JIE Wei GUO Junli |
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| Institution: | Hainan Provincial Key Laboratory for Tropical Cardiovascular Diseases Research, the First Affiliated Hospital of Hainan Medical University, Haikou, Hainan 571199, China;Hainan Provincial Key Laboratory for Tropical Cardiovascular Diseases Research, the First Affiliated Hospital of Hainan Medical University, Haikou, Hainan 571199, China;Key Laboratory of Emergency and Trauma of Ministry of Education Hainan Medical University & Research Unit of Island Emergency Medicine 2019RU013, Chinese Academy of Medical Sciences, Haikou, Hainan 571199, China |
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| Abstract: | Cardiovascular system development and cardiovascular disease are extremely complex process. Furin is an endonuclease and plays an important role in the development of cardiovascular system and the occurrence and progression of cardiovascular diseases. In this paper, the role of Furin in cardiovascular system development and cardiovascular diseases was reviewed, and the relationship between Furin and cardiovascular diseases was explored, which provides a new target for the prevention and treatment of various cardiovascular diseases. |
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| Keywords: | Furin cardiovascular system development cardiovascular diseases |
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