| 2008年广州市20岁以上正常人群甲型肝炎抗体流行率调查 |
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| 引用本文： | 吴小东,李文凡,杨生义,刘学恩,杨洁,周彬,庄辉,侯金林. 2008年广州市20岁以上正常人群甲型肝炎抗体流行率调查[J]. 广东寄生虫学会年报, 2010, 0(5): 551-552,566 |
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| 作者姓名： | 吴小东 李文凡 杨生义 刘学恩 杨洁 周彬 庄辉 侯金林 |
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| 作者单位： | [1]兰州大学第一临床医学院,兰州730000 [2]北京大学基础医学院病原生物学系,北京100083 [3]南方医科大学南方医院肝病中心,广州510515 |
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| 基金项目： | 国家自然科学基金（No.30872245） |
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| 摘 要： | 目的调查2008年广州市20岁以上正常人群甲型肝炎抗体（抗-HAV IgG）流行率。方法 2008年在广州市南方医院健康体检人群中,采集20岁以上5个年龄组正常人群血清500份,应用雅培（Abbott）公司抗-HAV IgG诊断试剂盒（化学发光法）,定性检测血清中的抗-HAV IgG,分析人群中抗-HAV IgG流行率。结果 2008年广州市20岁以上正常人群抗-HAV IgG总流行率为72.2%（361/500）,男性人群阳性率为73.2%（230/314）,女性人群阳性率70.4%（131/186）。20～岁组、30～岁组、40～岁组、50～岁组和60岁以上组抗-HAV IgG阳性率分别为52.8%（56/106）、52.5%（63/120）、82.5%（94/114）、89.8%（88/98）和96.8%（60/62）,随年龄增长而上升。结论目前广州市20～39岁组人群抗-HAV IgG阳性率较低,建议对该人群的易感者进行甲型肝炎疫苗免疫。
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| 关 键 词： | 甲型肝炎病毒 抗-HAV IgG 流行率 |
The Prevalent Rate of anti-HAV IgG in Normal Adults over 20 Years Old in Guangzhou in 2008 |
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| WU Xiao-dong,LI Wen-fan,YANG Sheng-yi,LIU Xue-en,YANG Jie,ZHOU Bin,ZHUANG Hui,HOU Jin-lin. The Prevalent Rate of anti-HAV IgG in Normal Adults over 20 Years Old in Guangzhou in 2008[J]. Journal of Tropical Medicine, 2010, 0(5): 551-552,566 |
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| Authors: | WU Xiao-dong LI Wen-fan YANG Sheng-yi LIU Xue-en YANG Jie ZHOU Bin ZHUANG Hui HOU Jin-lin |
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| Affiliation: | 1. College of First Clinical Medical,Lanzhou University,Lanzhou 730000; 2. College of Basic Medical,Peking University,Beijing 100083; 3. Institute of Hepatology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China) |
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| Abstract: | Objective To investigate the prevalent rate of anti-HAV IgG in normal adults over 20 years old in Guangzhou in 2008. Methods 500 sera were collected from normal adults for a routine medical examination in Nanfang Hospital in 2008. The Architect HAVAb-IgG （chemiluminescence method） was used for detection of anti-HAV IgG in serum,and the prevalent rates of anti-HAV IgG in the different age groups were evaluated. Results The prevalent rate of anti-HAV IgG in the population of age 20 in Guangzhou in 2008 was 72.2% （361 / 500）,in which 73.2% （230 / 314） for male,and 70.4%（131 / 186） for female. The prevalent rates of 20-,30-,40-,50-and ≥60 years age groups were 52.8% （56/106）,52.5% （63/120）,82.5% （94/114）,89.8% （88/98） and 96.8% （60 / 62）,respectively,with a trend of increasing with age. Conclusion At present,the prevalent rate of anti-HAV IgG is relatively low among the population age from 20 to 39 years old in Guangzhou. HAV vaccination should be recommended for the young adults susceptible to HAV infection. |
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| Keywords: | hepatitis A virus anti-HAV-IgG prevalence rate |
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