广州地区1226507例无偿献血者梅毒筛查结果分析

目的了解广州地区无偿献血者梅毒感染状况，确定梅毒感染低危人群，为安全输血提供有效的预防措施。方法选择广州地区2005—2009年无偿献血者梅毒筛查数据进行分析。梅毒血清学筛查试验采用ELISA试验，梅毒血清学筛查阳性标本采用TPPA试验确认。结果1226507例无偿献血者中梅毒阳性率为0．45％。其中单位员工、大专院校学生、流动人员和其他献血人员（包括无偿机采成分献血者）梅毒抗体阳性率分别为0．44％、0．14％、0．69％、0．29％；年龄在20～39岁梅毒抗体阳性献血者5126例，占梅毒抗体阳性者的93．4％；梅毒阳性率不同年龄和职业分布差异均有统计学意义（P〈0．01）。各年份无偿献血者中梅毒抗体阳性率差异无统计学意义（P〉0．05）。结论广州地区2005—2009年无偿献血人群梅毒感染率保持相对稳定水平，无明显上升趋势。大专院校学生和单位员工为梅毒感染低危人群，可作为主要献血人群，发展献血者队伍。采供血部门应加强对流动人员的无偿献血筛查工作，以保证血液安全。

Analysis of Syphilis Infection Status in 1 226 507 Blood Donors in Guangzhou

Objective To investigate the status of syphilis infection among the voluntary blood donors in Guangzhou, in order to ensure the safety supply of blood to the hospital. Methods Blood samples collected from 1 226 507 voluntary blood donors in Guangzhou from 2005 to 2009 were initially screened by TP-ELISA method. Positive samples were further confirmed by TPPA. Results 5 490 cases were found to be syphilis positive, and the positive rate was 0.45%.Of these 5 490 syphilis positive donors, 0.44% was government employees,0.14% was college students,0.69% was the floating population and 0.29% was other blood donors（including voluntary component apheresis donors）.5 126 donors were within the age of 20 to 39 years old,accounting for 93.4% of the syphilis positive donors. Positive rate of syphilis was significantly correlated with the age and occupation of the donors （P〈0.01）.Variation in the positive rate of infection between 2005 and 2009 was not observed （P〉0.05）. Conclusions The rate of syphilis infection in the volunteer blood donors was relatively stable between 2005 and 2009 in Guangzhou. College/university students and the government employees are the low risk group as blood donor.Blood collection departments should strengthen the screening of blood among the floating population to ensure blood safety.