Membrane-associated CD40L and sCD40L in atherothrombotic disease |
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| Authors: | Anand Sunil X Viles-Gonzalez Juan F Badimon Juan J Cavusoglu Erdal Marmur Jonathan D |
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| Institution: | The Zena and Michael A. Weiner Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York. USA. |
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| Abstract: | Recent data suggests that CD40L is involved in the pathogenesis of atherothrombotic disease. This review will focus on the history of CD40L, its role in platelet-mediated pathogenesis of atherothrombotic disease, its association to clinical syndromes and procedures, and its role in determining plaque rupture. |
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