氟比洛芬酯超前镇痛在整形外科中的应用

目的探讨氟比洛芬酯的超前镇痛效果以及超前镇痛在整形美容手术中的临床作用。方法40例吸脂手术患者随机分为氟比洛芬脂组（Ⅰ组，n=20）和对照组（Ⅱ组，n=20）。麻醉前30minⅠ组静脉注射氟比洛芬酯100mg，Ⅱ组静脉注射生理盐水10ml，采用疼痛程度视觉模拟评分（Visual analogue scale，VAS）法观测手术开始、手术结束时患者的疼痛程度并记录分析。结果手术开始时Ⅰ组与Ⅱ组两组样本t检验、结束时Ⅰ组与Ⅱ组两组样本t检验，p〈0．05，说明Ⅰ组与Ⅱ组比较，氟比洛芬酯在术中、术后具有明显减轻疼痛的效果。结论氟比洛芬酯具有良好的超前镇痛效果：在整形美容手术中应用超前镇痛的作用，能使患者在术中或术后减轻疼痛和恐惧感，提高患者对手术效果的满意度。

Application of Fiurbiprofen Axetil for Preemptive Analgesia During Plastic Surgery

Objective To discuss the preemptive analgesia effect of flurbiprofen axetil and the actions of using of preemptive analgesia in plastic Surgery. Methods 40 patients were randomly divided into two groups. The patients in group Ⅰ（n=20） received intravenous injection of flurbiprofen axetil 100 mg in 30 min before operation, and those in group Ⅱ （n= 20） intravenous injection of saline 10 ml. The degree of ache were evaluated by Visual Analogue Scale （VAS） at the beginning and end of the operation and the result was recorded and analysed, Results T test was used to compare the pain degree from the experimental and control group, and there was great significant difference between the experimental and control group at the beginning and end of operations （p〈0.05）. This meant flurbiprofen axetil can relieve the pain operatively and post-operatively. Conclusion flurbiprofen axetil has good preemptive analgetic effect. Preemptive analgesia can relieve pain and scares of patients operatively and post-operatively to improve the satisfaction of patients to operation effects in plastic surgeries.