胃肠动力药物在60例小肠胶囊内镜检查中的作用观察

目的 探讨胃肠动力药物对胶囊内镜检查中胶囊通过胃的时间、通过全小肠的时间的影响。方法收集2011年10月至2012年10月在我院行小肠胶囊内镜检查的60例患者，平均分成三组，A组检查前10min口服多潘立酮10mg，B组检查前10min口服莫沙比利10mg，C组检查前不服用任何药物。结果A组胶囊平均通过胃时间为24min±15min，B组平均通过胃时间为27min±20min，C组平均通过胃时间为45min±33min，多潘立酮、莫沙必利可以缩短胶囊在胃内的停留时间（P〈0．05）；A组胶囊平均通过小肠时间为6h±1h50min，B组平均通过小肠时间为3h40min±2h11min，C组平均通过小肠时间为6h30min±2h12min，B组与A组比较、B组与C组比较差异有统计学意义（P〈0．05），A组与C组比较差异无统计学意义（P〉0．05）。结论胶囊内镜检查前给予口服胃肠动力药可缩短胶囊在胃内的停留时间；胶囊内镜检查前给予口服莫沙必利可缩短胶囊通过全小肠的时间。

The Role and Observation of Gastrointestinal Motility Drugs in small bowel Capsule Endoscopy of 60 Cases

Objective To investigate the impact of gastrointestinal motility drug on the gastric transit time, complete small bowel transit time in capsule endoscopy. Methods Collected 60 cases of patients in small bowel capsule endoscopy in our hospital from October 2011 to October 2012, divided into three groups evenly, Group A： Oral domperidone 10mg10 minutes before the examination; Group B： oral mosapride 10mg 10 minutes before the examination; Group C： did not take any medication before the examination. Results Group A average gastric transit time of the capsule was 24 min -＋ 15 min, Group B average gastric transit time was 27rain ± 20min, Group C average gastric transit time was 45 min ＋ 33 min. Domperidone, mosapride can shorten the residence time of the capsule in the stomach （ P 〈 0.05 ） ; Group A average small bowel transit time of the capsule was 6 h ＋ 1 h50 min, Group B average small bowel transit time was 3 h40 min ＋ 2 hl 1 min, Group C average small bowel transit time was 6 h30 min ± 2 h12 min. ,Group B compared with Group A, Group B compared with Group C, the differences were statistically significant （P 〈 0.05 ） ; Group A compared with Group C, the difference was not statistically significant （ P 〉 0.05 ）. Conclusion Prior to capsule endoscopy the oral gastrointestinal drugs can shorten the residence time of the capsule in the stomach; oral mosapride before capsule endoscopy can shorten the time the capsule went through the small bowel.