高龄冠心病患者血清脑利钠肽、左室射血分数与心功能分级的相关性研究

目的研究脑利钠肽、左室射血分数与80岁以上高龄冠心病患者心功能的关系。方法方差分析222例患者各心功能分级之间脑利钠肽、左室射血分数的差异,并行相关分析。结果①心功能分级与脑利钠肽正相关,不同心功能分级患者脑利钠肽差异有统计学意义(r=0.512,P<0.05);②心功能分级与左室射血分数负相关,不同心功能分级患者左室射血分数差异有统计学意义(r=-0.555,P<0.05)。结论脑利钠肽、左室射血分数与心功能分级有相关关系,但均不能作为诊断心功能分级的唯一标准。

Study on the relationship between serum brain natriuretic peptide,left ventricular ejection fraction and cardiac function in senile patients with coronary heart disease

Objective To investigate the relationship between serum brain natriuretic peptide（BNP）,left ventricular ejection fraction（LVEF） and cardiac function in more than 80-year-old patients with coronary heart disease.Methods Serum BNP,LVEF and each cardiac functional class in 222 patients were analyzed with variance analysis method.Correlation analysis was carried out at the same time.Results The cardiac functional class was positively correlated with the serum BNP.The serum BNP levels had a statistically significant differences in patients with different cardiac functional class.The cardiac functional class was negatively correlated with the LVEF.The LVEF had a statistically significant difference in patients with different cardiac functional class.Conclusion The serum BNP and LVEF correlate with cardiac functional class,but neither of them may be a unique diagnosis standard of cardiac functional class.