空腹血糖和餐后2h血糖诊断糖代谢异常的一致性分析

目的比较空腹血糖(FBG)和口服葡萄糖耐量试验(OGTT)后2 h血糖(2 h BG)诊断糖尿病前期和糖尿病的一致性。方法收集在安徽省立医院健康体检中心和门诊进行OGTT检测的1280例受试者,按其FBG及2 hBG水平分为5组,并行Kappa一致性比较检测两者诊断糖尿病前期和糖尿病的能力。结果1280例受试者中,有843例糖耐量正常者(65.9%),251例新诊断的糖尿病前期患者(19.6%)及186例新诊断糖尿病者(14.5%);FBG和2 hBG在诊断糖尿病前期及糖尿病人群时,Kappa值分别为0.305和0.790;与FBG相比,2 h BG可以诊断出更多的糖尿病及糖尿病前期患者。结论联合FBG和2 h BG检测可以提高糖代谢异常,尤其是糖尿病前期患者的检出率。

Consistency of fasting blood glucose and OGTT 2h blood glucose for diagnosing prediabetes and diabetes

Objective To compare the prediabetes and diabetes diagnosis rate based on fasting blood glucose（FBG） and OGTT 2h blood glucose measurement（2hBG）.Methods FBG and 2hBG were tested among 1280 adults without known diabetes and impaired glucose regulation obtained from Anhui Provincial Hospital Health Examination Center and the clinic.The subjects were divided into 5 groups according to FBG and 2hBG levels.The Kappa agreement was used to compare the prediabetes and diabetes diagnosis rate based on FPG and 2hBG.Results The prevalence rates of normal gluose tolerance（NGT,N=843）,impaired glucose regulation（IGR,N=251） and diabetes（DM,N=186） were 65.9%,19.6% and 14.5% among 1280 subjects,respectively.The Kappa values were 0.305 and 0.790 of fasting blood glucose and OGTT 2h blood glucose for diagnosing prediabetes and diabetes.Compared with FBG,2hBG can diagnose more patients with prediabetes and diabetes.Conclusion The combined FBG and 2 hBG can increase the detection rate of prediabetes and diabetes,especially for prediabetes.