针刺对子宫内膜异位症模型鼠镇痛机制的影响

目的 :探讨针刺对子宫内膜异位症的镇痛机制的影响。方法 :SD大鼠 30只随机分为空白对照组、模型对照组、针刺治疗组。并分别监测各组大鼠血及内膜前列腺素PGF1α,PGE2 含量 ;血清Ca+ + ,K+ ,Na+ ,Cl-含量。结果 :与正常组比较 ,模型组血及内膜PGE2 含量明显降低 ,PGF1α含量显著升高 ,血清Ca+ + 下降 ,而Na+ 、Cl-、K+ 则呈上升趋势 ;与模型组比较 ,针刺治疗组血及内膜PGE2 含量明显升高 ,PGF1α含量显著降低 ,血清Ca+ + 、Na+ 、Cl-、K+ 数值均趋于正常组。结论 :针刺能通过对EMT大鼠的整体调节而达其镇痛疗效

The Effect of the Analgesia Mechanism of Acupuncture Therapy on Treating Endometriosis

Objective :To investigate the analgesia mechanism of acupuncture therapy on treating endometriosis(EMT). Methods :30 SD rats were divided into three groups as the normal group,EMT model group,acupuncture group.The level of PGF 1α and PGE 2 in blood and endometrium were detected;and the content of Ca 2+ ,K +,Na +,Cl - in serum were checked. Results :Compared with normal group,the EMT model group has decreased clearly the content of PGE 2 in blood and endometrium,and increased significantly the content of PGF 1α ;the content of Ca 2+ in serum has been reduced ;but the content of Na +,Cl -,K + in serum has been increased.Compared with the EMT model group,acupuncture group increased clearly the content of PGE 2,decreaased the content of PGF 1α ,and the content of Ca 2+ ,Na +,Cl -,K + were also in normal level. Conclusion :Acupuncture therapy has its analgesia function on EMT rats by regulating the whole mechanism of EMT rats.