| 尿羟脯氨酸氨基多糖与大骨节病临床早期体征关系的研究 |
| |
| 引用本文： | 张矢远,郭雄,莫晓燕,于志道. 尿羟脯氨酸氨基多糖与大骨节病临床早期体征关系的研究[J]. 中国地方病学杂志, 1993, 0(1) |
| |
| 作者姓名： | 张矢远 郭雄 莫晓燕 于志道 |
| |
| 作者单位： | 西安医科大学地方性骨病研究所(张矢远，郭雄，莫晓燕)，西安医科大学地方性骨病研究所(于志道) |
| |
| 摘 要： | 本文对大骨节病临床早期体征指末弯、指关节增粗及手部 X 线异常改变,与尿液中羟脯氨酸、氨基多糖合量之间关系作了分析。结果表明,随着临床体征及 X 线干骺端、骨端异常改变的加剧,尿羟脯氨酸、氨基多糖含量相应降低,与正常组有十分显著差异(P<0.01),因此认为尿羟脯氨酸、氨基多糖要作为大骨节病早期诊断中颇有意义的生化指标。
|
| 关 键 词： | 大骨节病 指末弯 干骺端异常 羟脯氨酸 氨基多糖 |
Study on the relationship between hydroxyproline,glycosaminoglcan and the clinical early signs of Kashin-Beck Disease |
| |
| Zhang Shiyuan,et al. Study on the relationship between hydroxyproline,glycosaminoglcan and the clinical early signs of Kashin-Beck Disease[J]. Chinese Jouranl of Endemiology, 1993, 0(1) |
| |
| Authors: | Zhang Shiyuan et al |
| |
| Abstract: | We explored the relationship between early flexion of distal joint of fingers,enlargement of finger joints and ab-normal X-ray changes in Kashin-Beck disease and the urinary excretion of hydroxyproline and glycosaminogly-can.The results showed that the amount of hydroxyproline and glycosaminoglycan in urine was significantly de-creased(p<0.01)as the clinical signs and abnormal X-ray changes in metaphysis become marked.Therefore theseresults suggested that hydroxyproline and glycosaminoglycan in urine could be the biochemical index for diagnosis ofKashin-Beck disease in the early stage. |
| |
| Keywords: | Kashin-Beck disease flexion of the terminal part of the fingers X-ray In metaphysis hydroxyproline glycosaminoglycan |
| 本文献已被 CNKI 等数据库收录！ |
