Obesity in early onset breast cancer in African American patients |
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Authors: | Ida Micaily MD Hannah Hackbart Meghan Butryn PhD Maysa M. Abu-Khalaf MD |
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Affiliation: | 1. Department of Medical Oncology, Thomas Jefferson University, Sidney Kimmel Cancer Center at Jefferson Health, Philadelphia, Pennsylvania, USA;2. Sidney Kimmel Medical College, Philadelphia, Pennsylvania, USA;3. Department of Psychology and Center for Weight, Eating, and Lifestyle Science, Drexel University, Philadelphia, Pennsylvania, USA |
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Abstract: | Obesity is a modifiable risk factor in breast cancer patients and is predictive of disease outcomes in early-onset breast cancer survivors. The purpose of this review is to summarize the current evidence in the association between early-onset breast cancer and obesity, specifically in African-American women. Reviewing the molecular mechanisms and social determinants of disease in this population can provide a foundation for future interventions in prevention, detection, and treatment aiming at improving outcomes for young breast cancer patients. |
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Keywords: | AAF breast cancer lifestyle modification obesity TNBC triple-negative |
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