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Obesity in early onset breast cancer in African American patients
Authors:Ida Micaily MD  Hannah Hackbart  Meghan Butryn PhD  Maysa M. Abu-Khalaf MD
Affiliation:1. Department of Medical Oncology, Thomas Jefferson University, Sidney Kimmel Cancer Center at Jefferson Health, Philadelphia, Pennsylvania, USA;2. Sidney Kimmel Medical College, Philadelphia, Pennsylvania, USA;3. Department of Psychology and Center for Weight, Eating, and Lifestyle Science, Drexel University, Philadelphia, Pennsylvania, USA
Abstract:Obesity is a modifiable risk factor in breast cancer patients and is predictive of disease outcomes in early-onset breast cancer survivors. The purpose of this review is to summarize the current evidence in the association between early-onset breast cancer and obesity, specifically in African-American women. Reviewing the molecular mechanisms and social determinants of disease in this population can provide a foundation for future interventions in prevention, detection, and treatment aiming at improving outcomes for young breast cancer patients.
Keywords:AAF  breast cancer  lifestyle modification  obesity  TNBC  triple-negative
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