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Demographic and clinical characteristics of familial and sporadic multiple sclerosis: A single center exploratory study from Abu Dhabi
Affiliation:1. Department of Experimental Medicine, University of Perugia, Perugia, Italy;2. Neurologist, Perugia, Italy;3. Department of Philosophy, Social Sciences and Education, University of Perugia, Italy;4. Department of Medicine, University of Perugia, Perugia, Italy;5. Degree Course in Speech and Language Therapy, University of Perugia, Perugia, Italy;6. Department of Neuroscience, “Santa Maria” Hospital, Terni, Italy;1. Laboratory of Clinical Neurodegenerative Diseases, National Institute of Neurology and Neurosurgery of Mexico, Insurgentes Sur # 3877, CP 14269 Mexico City, Mexico;2. Genetics and Neuroimmunology Laboratory, National Institute of Medical Sciences and Nutrition, Periférico Sur # 4809, CP 14610 Mexico City, Mexico;3. Genetics Laboratory, National Institute of Neurology and Neurosurgery of Mexico, Insurgentes Sur # 3877, CP 14269 Mexico City, Mexico;1. Department of Neurosurgery, Stanford University, Stanford, CA, United States;2. Department of Neurosurgery, University Hospital Zurich & Clinical Neuroscience Center, University of Zurich, Switzerland;3. Department of Medicine, Division of Oncology, Stanford University, Stanford, CA, United States;4. Department of Pathology, Stanford University, Stanford, CA, United States;1. Department of Radiation Oncology, Kaiser Los Angeles Medical Center, 4950 Sunset Blvd, Los Angeles, CA 90027, USA;2. Department of Interventional Radiology, Kaiser Los Angeles Medical Center, 4867 Sunset Blvd, Los Angeles, CA 90028, USA;3. Department of Neurological Surgery, Kaiser Los Angeles Medical Center, 1505 N Edgemont St, Los Angeles, CA 90027, USA;4. Department of Neurological Surgery, Keck School of Medicine of USC, 1200 N State St, Suite 3300, Los Angeles, CA 90033, USA;1. Department of Orthopaedic Surgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan;2. Department of Neurosurgery, Shinshu University Hospital, Matsumoto, Japan;3. Center for Medical Genetics, Shinshu University Hospital, Matsumoto, Japan;4. Department of Spinal Surgery, Kameda Medical Center, Kamogawa, Japan
Abstract:Demographic and clinical characteristics of Familial Multiple Sclerosis (FMS) have not been fully investigated yet in Abu Dhabi. The aim of this single center exploratory study was to investigate demographic and clinical characteristics of FMS compared to sporadic MS (SMS) in Abu Dhabi.A chart review single center study was conducted in 98 patients with MS. Group comparisons were performed using Mann-Whitney and Chi-Square tests as appropriate. A p < 0.05 was considered statistically significant. 24.5% were patients with FMS and 83% were Emirates. No significant differences in demographic and clinical characteristics were found between patients with FMS and SMS in overall all MS patients and in the Emirati group analyzed alone.Patients with FMS did not differ in demographic and clinical characteristics compared to patients with SMS. Further prospective studies are needed to elucidate environmental and genetic risk factors contributing to FMS in the Emirati population.
Keywords:Familial multiple sclerosis  Sporadic multiple sclerosis  Emirati  Expatriates  Age at onset
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