Gone in the blink of an eye – A Tolosa-Hunt syndrome variant |
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Institution: | 1. Department of Neurosciences, Santa Maria della Misericordia University Hospital, Udine, Italy;2. Department of Medical and Biological Sciences, Institution of Anatomic Pathology, Santa Maria della Misericordia University Hospital, Udine, Italy;3. French Reference Center of Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Synatac Team, NeuroMyoGene Institut, INSERM U1217/CNRS UMR5310, University Claude Bernard Lyon 1, Lyon, France |
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Abstract: | Tolosa-Hunt syndrome is a rare disorder characterized by severe peri-orbital headache and ophthalmoplegia resulting from pseudotumour in the cavernous sinus compressing structures within it, namely cranial nerves III, IV, and VI and the superior divisions of cranial nerve V. We report the case of a 47 year old female who presented with painless left unilateral ptosis and complete external ophthalmoplegia. Magnetic Resonance Imaging (MRI) identified an enhancing heterogeneous mass filling the left cavernous sinus, following the course of the oculomotor nerve. After 2 weeks symptoms and signs resolved and there was a parallel resolution of the MRI findings, without the administration of corticosteroids. As far as we are aware this is one of the first reports of Tolosa-Hunt syndrome variant, with painless neurological involvement confined solely to the oculomotor nerve, and with complete resolution without pharmacological intervention. |
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Keywords: | Tolosa–Hunt syndrome Tolosa–Hunt variant Ophthalmoplegia Oculomotor nerve |
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