Approach to critical illness myopathy and polyneuropathy in the older SARS-CoV-2 patients |
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| Institution: | 1. Lake Erie College of Osteopathic Medicine, United States;2. Penn State College of Medicine, United States;3. Touro College of Osteopathic Medicine, United States;4. Department of Internal Medicine, Penn State Milton S. Hershey Medical Center, United States;5. University College of Medical Sciences, Delhi, India;6. Department of Internal Medicine, KISTMC, Tribhuvan University, Nepal, India;7. Department of Pediatrics and Neurology, Penn State Milton S. Hershey Medical Center, United States |
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| Abstract: | One of the major concerns of the health care community and the public surrounding the SARS-CoV-2 pandemic is the availability and use of ventilators. Unprecedented surges of patients presented to intensive care units across the country, with older adults making up a large proportion of the patient population. This paper illustrates contemporary approaches to critical illness myopathy (CIM), critical illness polyneuropathy (CIP), and critical illness polyneuromyopathy (CIPNM) in older patients, including incidence, risk factors, mechanisms for pathology, diagnosis, contemporary treatment approaches, and outcomes. We hope that the following analysis may help educate clinicians and ultimately decrease the duration of the mechanical ventilation required by these patients, resulting in improved clinical outcomes and an increase in ventilator availability for other patients in need. |
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| Keywords: | SARS-CoV-2 COVID-19 Critical illness myopathy Critical illness polyneuropathy Intensive care unit-acquired weakness Older adults |
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