Aggressive course of cognitive impairment in multiple sclerosis: A new term for the management of patients |
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| Affiliation: | 1. Division of Neurology, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada;2. Department of Neurosciences and Mental Health, SickKids Research Institute, Toronto, Ontario, Canada;1. Department of Neurology and Center of Clinical Neuroscience, Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic;2. Buffalo Neuroimaging Analysis Center, Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA;3. IRCCS “S.Maria Nascente”, Don Gnocchi Foundation, Milan, Italy;4. Department of Radiology Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic;5. MR Imaging Clinical Translational Research Center, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA |
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| Abstract: | Multiple sclerosis (MS) can create different kinds of symptoms by involving different fields of the central nervous system. Cognitive impairment (CI) is one of the symptoms that can be caused by the onset of the disease and provide a change in the patient’s quality of life. Considering the course of the disease, CI usually worsens increasingly, and there is usually a severe CI in patients with end stage of MS. However, progressing CI can be so fast and severe in a few patients that it can disrupt the daily affairs of the individual. This paper plans to define the aggressive course of CIs in MS patients according to the reported cases. This definition explains that, the aggressive course of CI in MS patients happens in less than 5 years from the onset of the disease, and during this time, it causes dementia in the patient. |
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| Keywords: | Aggressive course Cognitive impairment Multiple sclerosis |
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