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Successful intravenous thrombolysis for ischemic stroke as a complication of coronary intervention in patients with ticagrelor pretreatment
Affiliation:1. Department of Neurology, Christchurch Hospital, Christchurch, New Zealand;2. Department of Cardiology, Christchurch Hospital, Christchurch, New Zealand;3. Department of Neurosciences, Box Hill Hospital, Eastern Health, Melbourne, Australia;4. Eastern Health Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia;1. University of Florida, Department of Pediatrics, Division of Neurology, 1600 SW Archer Road, Gainesville, FL 32608, United States;2. University of Florida Jacksonville, Department of Neurology, United States;1. Department of Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia;2. Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia;3. Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Victoria, Australia;1. Nuffield Department of Surgical Sciences, John Radcliffe Hospital, Oxford, UK;2. Department of Neurosurgery, Level 3, The West Wing, John Radcliffe Hospital, Oxford, UK
Abstract:Ticagrelor is an antiplatelet agent used for treatment of coronary artery disease via inhibition of the P2Y12 receptor. Based on limited literature the safety of intravenous thrombolysis for ischemic stroke in patients with ticagrelor pretreatment is unknown. We present two patients established on ticagrelor treated with intravenous thrombolysis for acute ischemic stroke complicating coronary intervention.
Keywords:Ischemic stroke  Ticagrelor  Thrombolysis
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