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ETH患者淋巴细胞亚群及红细胞免疫功能的研究
引用本文:任黎明 王洪清. ETH患者淋巴细胞亚群及红细胞免疫功能的研究[J]. 实用全科医学, 2005, 3(6): 515-515,517
作者姓名:任黎明 王洪清
作者单位:山东省滕州市中心人民医院,277500
摘    要:目的 探讨流行性出血热(EHF)患者机体细胞免疫功能。方法 检测流行性出血热患者外周血CD3^+,CD4^+,CD8^+,CD4^+/CD8^+及红细胞免疫粘附功能。取患者50人,正常人对照20人。结果 与正常对照相比较,患者外周血CD3^+,CD4^+,CD8^+,CD4^+/CD8^+及红细胞免疫粘附功能降低,CD8^+明显增高(均P〈0.01)。随病情的好转,CD3^+,CD4^+,CD8^+,CD4^+/CD8^+及红细胞免疫粘附功能逐渐趋于正常。结论 流行性出血热患者细胞免疫功能低下与其发病主要机制有关。

关 键 词:淋巴细胞亚群 红细胞 免疫功能 流行性出血热 发病机制
收稿时间:2005-03-21
修稿时间:2005-03-21

Immune Function of T-lymphcyte Subgroup and Erythrocyte in Epidemic Hemorrhegic Fever
REN Liming, WANG Hongqing. Immune Function of T-lymphcyte Subgroup and Erythrocyte in Epidemic Hemorrhegic Fever[J]. Applied Journal Of General Practice, 2005, 3(6): 515-515,517
Authors:REN Liming   WANG Hongqing
Abstract:Objective To investigate the cellular immune function in human epidemic hemorrhagic fever (EHF). Methods The peripheral blood CD3+,CD4+,CD8+,CD4+/CD8+ and erythrocyte immune adhesion function were mensurated in 50 cases with EHF and 20 normal individuals as control. Results The peripheral blood CD_3~+,CD_4~+,CD_4~+/CD_8~+ and erythrocyte immune adhesion function decreased,but CD_8~+ increased in the treatment group compared with the control group. Each index approximated to normal as the status was improved. Conclusions The pathogenesis of BHF is tightly associated the hypofunction of cellular immune.
Keywords:Epidemic hemorrhagic fever   T - lymphocyte subgroup   Erythrocyte immune adhesion function
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