The link between allergic rhinitis and asthma: A role for antileukotrienes? |
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| Authors: | H Kim J Bouchard PM Renzix |
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| Affiliation: | 1McMaster University, Hamilton, Ontario;2University of Western Ontario, London, Ontario;3St Joseph’s Hospital, La Malbaie, Quebec;4University of Montreal, Montreal, Quebec |
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| Abstract: | Allergic rhinitis and asthma are both chronic heterogeneous disorders, with an overlapping epidemiology of prevalence, health care costs and social costs in quality of life. Both are inflammatory disorders with a similar pathophysiology, and both share some treatment approaches. However, each disorder has an array of treatments used separately in controlling these atopic disorders, from inhaled corticosteroids, beta2-agonists and antihistamines to newer monoclonal antibody-based treatments. The present article reviews the shared components of allergic rhinitis and asthma, and examines recent evidence supporting antileukotrienes as effective agents in reducing the symptoms of both diseases. |
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| Keywords: | Antileukotrienes Asthma Epidemiology Pathophysiology Rhinitis |
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