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The TRH stimulation test and the dexamethasone suppression test in depression
Authors:H Dam  E T Mellerup  O J Rafaelsen
Affiliation:1. Department of Veterinary Microbiology, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa, 252-5201, Japan;2. Fujimura Animal Hospital, 5-10-26, Aomatanihigashi, Minou, Osaka, 562-0022, Japan;3. Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA;1. College of Science, Massey University, Palmerston North, New Zealand;2. Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada;3. Otago Genomics and Bioinformatics Facility, Otago University, Dunedin, New Zealand;1. Pathobiology, School of Veterinary Science, Massey University, Palmerston North, New Zealand;2. Gansu Agricultural University, Lanzhou, China;3. Gribbles Veterinary Pathology, Palmerston North, New Zealand;1. Sub-Department of Clinical Diagnostics and Veterinary Dermatology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Lublin, Poland;2. Equine Breeding and Management Unit, Department of Biology and Animal Breeding, University of Life Sciences in Lublin, Lublin, Poland;3. Department of Internal Diseases, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Lublin, Poland;1. Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 704, Taiwan;2. Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, 704, Taiwan;3. Division of Infectious Diseases, Department of Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 704, Taiwan;4. Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, 704, Taiwan
Abstract:The thyrotropin-releasing hormone (TRH) stimulation test and the dexamethasone suppression test (DST) were performed in 40 depressive patients. More endogenously depressed patients than nonendogenously depressed patients showed a blunted response to TRH. No difference was found in delta max thyroid-stimulating hormone (TSH) between patients who responded to dexamethasone administration with a normal suppression of cortisol and those who responded with nonsuppression.
Keywords:
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