| 住院患者中药物性肾病的可疑药物筛选 |
| |
| 引用本文： | 姜慧芳,程能能,杜文民. 住院患者中药物性肾病的可疑药物筛选[J]. 中国临床药学杂志, 2011, 0(6): 359-361 |
| |
| 作者姓名： | 姜慧芳 程能能 杜文民 |
| |
| 作者单位： | 复旦大学药学院药理学教研室;上海市药品不良反应监测中心; |
| |
| 摘 要： | 目的探讨药物性肾病在我国住院患者人群中发生率及与筛选出其可疑药物。方法利用2009年5月29日至12月31日医院住院患者用药数据库(IDUD)信息,采用数据挖掘技术结合药物流行病学研究方法,计算药物性肾病与可疑药物之间相对危险度。结果共获得药物性肾病的可疑药物130个,其中中药49个。按相对危险度排序,前3位可疑药物分别为扶正化瘀、肾衰宁和精氨酸。结论在住院患者人群中,特别是使用中药的患者,应加强肾功能监测。
|
| 关 键 词： | 药物性肾病 中药 可疑药物 相对危险度 |
Suspected drug screening of drug-induced renal disease in inpatients population |
| |
| JIANG Huifang,CHENG Nengneng,DU Wenmin. Suspected drug screening of drug-induced renal disease in inpatients population[J]. Chinese Journal of Clinical Pharmacy, 2011, 0(6): 359-361 |
| |
| Authors: | JIANG Huifang CHENG Nengneng DU Wenmin |
| |
| Affiliation: | JIANG Huifang~1,CHENG Nengneng~1,DU Wenmin~2(1 Department of Pharmacology,School of Pharmacy,Fudan University,Shanghai 201203,China,2 Shanghai Center for Adverse Drug Reactions Monitoring,Shanghai 200233,China) |
| |
| Abstract: | AIM To investigate the incidence rate and suspected drugs of drug-induced renal disease in inpatients population.METHODS Based on Shanghai inpatients drug utilization database(from May 29,2009 to December 31, 2009) we used data mining technology and methods in pharmacoepidemiology to calculate the odds ratio(OR) of suspected drug in inducing renal disease.RESULTS A total of 130 drugs were suspected as renal disease inducing drugs,a- mong them 49 drugs were Chinese traditional medicine.First 3 drugs on the O... |
| |
| Keywords: | drug-induced renal disease Chinese traditional medicine suspected drug odds ratio |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
