首页 | 本学科首页   官方微博 | 高级检索  
     


Oxidative and carbonyl stress in patients with obstructive sleep apnea treated with continuous positive airway pressure
Authors:Peter Celec  Július Hodosy  Michal Behuliak  Roland Pálffy  Roman Gardlík  Luká? Hal?ák  Imrich Mucska
Affiliation:1. Institute of Molecular Biomedicine, Comenius University, Sasinkova 4, 811 08, Bratislava, Slovakia
2. Institute of Pathophysiology, Comenius University, Bratislava, Slovakia
3. Department of Molecular Biology, Comenius University, Bratislava, Slovakia
4. Institute of Physiology, Comenius University, Bratislava, Slovakia
5. Institute of Molecular Biomedicine, Comenius University, Bratislava, Slovakia
6. Institute of Chemistry, Biochemistry and Clinical Biochemistry, Comenius University, Bratislava, Slovakia
7. Sleep Laboratory, University Hospital, Comenius University, Bratislava, Slovakia
Abstract:

Purpose  

The pathogenesis of cardiovascular complications of obstructive sleep apnea syndrome (OSAS) can be explained by oxidative and carbonyl stress due to oxygenation and reoxygenation injury during sleep. This hypothesis has yet to be proved experimentally, although several clinical observations have found increased oxidative damage in plasma. Continuous positive airway pressure (CPAP) improves symptoms and prognosis of patients with OSAS.
Keywords:
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号