Novel Implant Design Improves Implant Survival in Multirooted Extraction Sites: A Preclinical Pilot Study

Background: The primary aim is to evaluate clinical, radiographic, and histologic parameters of novel implants with “three roots” design that were inserted into fresh multirooted extraction sockets. A secondary aim is to compare this new implant to standard root‐form dental implants. Methods: Immediate implantation of novel or standard design 6 × 6‐mm implants was performed bilaterally into multirooted sockets in mandibles of mini‐pigs. Twelve weeks later, clinical, radiographic, stability, histomorphometric, and microcomputed tomography (micro‐CT) analyses were performed. Results: Survival rates were significantly higher in the test implants compared with control (92.8% versus 33.3%, respectively; P <0.001). Bone loss was greater in the control compared with the test by sounding (mean 3.42 ± 0.68 versus 1.96 ± 0.34 mm) and radiography (mean 3.35 ± 0.62 versus 2.27 ± 0.33 mm). Histologic and micro‐CT analyses demonstrated bone fill in the inner part of the test implants. Moreover, bone‐to‐implant contact was higher in the test implants (55.50% ± 3.68% versus 42.47% ± 9.89%). Contrary to the clinical, radiographic, and histomorphometric results, resonance frequency analysis measurements were greater in the control group (77.74 ± 3.21 implant stability quotient ISQ]) compared with the test group (31.09 ± 0.28 ISQ), P = 0.008. Conclusions: The novel design implants resulted in significantly greater survival rate in multirooted extraction sites. Further studies will be required to validate these findings.